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COMPLEMENT C5A, DES-ARGININE
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DeCS
Descriptor
English
:
Complement C5a, des-Arginine
Descriptor
Spanish
:
Complemento C5a des-Arginina
Descriptor
Portuguese
:
Complemento C5a des-Arginina
Tree Number:
D12.776.124.486.274.024.270.255
D12.776.124.486.274.450.250.255
Definition
English
:
A derivative of
complement C5a
, generated when the carboxy-terminal
ARGININE
is removed by
CARBOXYPEPTIDASE B
present in normal human serum. C5a des-Arg shows complete loss of spasmogenic activity though it retains some chemotactic ability (CHEMOATTRACTANTS).
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006 (1990)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
24581
Unique Identifier:
D015937
Occurrence in VHL
:
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CID-10
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